There’s something magical about warm, gooey pepperoni cheese bread fresh from the oven – it’s like pizza’s cooler cousin decided to show up to the party. This pepperoni cheese bread recipe delivers restaurant-quality results at home, with stretchy mozzarella, savory pepperoni, and a golden crust that’ll have everyone asking for your secret.
SERVES: 4 | PREP: 20 MIN | COOK: 25 MIN | TOTAL: 45 MIN
Ingredients You’ll Need
For the Dough Base
| Ingredient | Measurement |
|---|---|
| Warm water (110°F) | 1 cup |
| Active dry yeast | 2¼ tsp (1 packet) |
| Sugar | 1 tbsp |
| All-purpose flour | 3 cups |
| Salt | 1 tsp |
| Olive oil | 2 tbsp |
For the Filling
| Ingredient | Measurement |
|---|---|
| Shredded mozzarella cheese | 2 cups |
| Pepperoni slices | 1½ cups (about 60 slices) |
| Garlic powder | 1 tsp |
| Italian seasoning | 1 tsp |
| Red pepper flakes | ½ tsp |
For the Topping
| Ingredient | Measurement |
|---|---|
| Melted butter | 3 tbsp |
| Minced garlic | 2 cloves |
| Grated Parmesan cheese | ¼ cup |
| Fresh parsley (chopped) | 2 tbsp |
Step-by-Step Instructions
Phase 1: Activating the Dough (10 minutes)
Step 1: Pour your warm water into a large mixing bowl. The water should feel like a comfortable bath – if it’s too hot, it’ll kill the yeast, and too cold means it won’t activate properly.
Step 2: Sprinkle the yeast and sugar over the water, then give it a gentle stir. Let this mixture sit for 5-7 minutes until it gets foamy and bubbly on top. This foam tells you the yeast is alive and ready to work its magic.
Step 3: Add the olive oil to your yeast mixture and stir it in. The oil keeps your dough tender and prevents it from drying out during baking.
Step 4: Mix the flour and salt together in a separate bowl first. This ensures the salt distributes evenly – if salt touches yeast directly, it can slow down the rising process.
Phase 2: Building the Dough (8 minutes)
Step 5: Add the flour mixture to your yeast mixture one cup at a time, stirring after each addition. You’ll notice the dough getting thicker and harder to stir – that’s exactly what you want.
Step 6: Once the dough becomes too thick to stir, turn it out onto a floured surface. Your hands are now your best tools. Knead the dough for 5-6 minutes until it’s smooth and elastic. You’ll know it’s ready when you poke it and the indent slowly springs back.
Step 7: Shape the dough into a ball and place it in a lightly oiled bowl. Cover with a clean kitchen towel and let it rise in a warm spot for 15 minutes. This short rise gives the dough just enough puff without making you wait forever.
Phase 3: Assembly Time (7 minutes)
Step 8: Punch down your risen dough (this releases excess air) and roll it out on a floured surface into a 12×16 inch rectangle. The rectangle shape makes rolling and slicing much easier than a circle.
Step 9: Spread your shredded mozzarella evenly across the entire surface, leaving a ½-inch border around all edges. This border acts like a seal when you roll it up.
Step 10: Layer your pepperoni slices over the cheese, slightly overlapping them. I like to cover every inch – nobody wants a bite without pepperoni! Sprinkle the garlic powder, Italian seasoning, and red pepper flakes evenly over everything.
Step 11: Starting from the long side, tightly roll the dough into a log shape. Pinch the seam closed as you roll to prevent cheese from leaking out during baking. Place your roll seam-side down on a parchment-lined baking sheet.
Phase 4: Final Touches and Baking (25 minutes)
Step 12: Mix your melted butter with minced garlic and brush this mixture generously over the top of your roll. This creates that irresistible golden crust we’re after.
Step 13: Sprinkle the Parmesan cheese over the buttered surface. Some will fall off onto the pan – that’s okay! Those bits will get crispy and delicious.
Step 14: Using a sharp knife, make 3-4 shallow diagonal cuts across the top of your bread. These vents let steam escape and give you that professional bakery look.
Step 15: Bake at 375°F for 22-25 minutes until the top is golden brown and the cheese is bubbling out slightly from the cuts. Your kitchen will smell incredible right now.
Step 16: Remove from the oven and immediately sprinkle with fresh parsley. Let it cool for 5 minutes before slicing – this rest time lets the cheese set slightly so your slices stay intact.
Chef’s Notes
Yeast Temperature Matters: I always test my water temperature with an instant-read thermometer. Between 105-115°F is the sweet spot. Too hot kills the yeast, too cold and it won’t activate. If you don’t have a thermometer, the water should feel warm but not uncomfortable on your wrist.
Cheese Selection Strategy: While mozzarella is traditional for pepperoni cheese bread, I’ve found that mixing in ½ cup of provolone adds a sharper flavor that really complements the pepperoni. Some folks even add a handful of cheddar for extra punch.
Pepperoni Prep Tip: Pat your pepperoni slices with a paper towel before adding them to remove excess grease. This prevents your bread from getting soggy and keeps the bottom crust crispy. If you’re using thick-cut pepperoni, chop it into smaller pieces for easier eating.
The Rolling Technique: When you roll your dough, apply gentle but firm pressure. You want it tight enough that there aren’t air pockets, but not so tight that you squeeze out all the cheese. Think of it like rolling a sleeping bag – snug but not strangling.
Nutrition Information (Per Serving)
| Nutrient | Amount |
|---|---|
| Calories | 485 |
| Protein | 22g |
| Carbohydrates | 48g |
| Fat | 22g |
| Fiber | 2g |
| Sodium | 980mg |
Creative Variations to Try
Supreme Pizza Bread: Add sautéed bell peppers, onions, and mushrooms along with your pepperoni and cheese. The vegetables add moisture and nutrients without sacrificing any flavor. Similar to how potato bread incorporates vegetables for extra texture, these additions make your bread more substantial.
Spicy Jalapeño Version: Replace half the pepperoni with pickled jalapeño slices and use pepper jack cheese instead of mozzarella. Brush the top with garlic butter mixed with sriracha for an extra kick that heat-lovers will devour.
Meat Lover’s Twist: Combine pepperoni with cooked Italian sausage and crispy bacon bits. This protein-packed version turns your pepperoni cheese bread into a complete meal that satisfies the heartiest appetites.
Italian Herb Garden Style: Skip the pepperoni and load up with fresh basil, sun-dried tomatoes, and a blend of mozzarella and ricotta cheese. Just like panettone features fruit and citrus for a sweeter profile, this variation celebrates fresh Italian herbs for a lighter option.
Storage & Reheating Guide
Room Temperature: Your pepperoni cheese bread stays fresh at room temperature for up to 8 hours wrapped in aluminum foil. This works great if you’re serving it for a party or game day.
Refrigerator Storage: Wrap cooled bread tightly in plastic wrap, then foil, and refrigerate for up to 4 days. The double wrap prevents it from drying out and keeps other fridge odors away.
Freezing Instructions: Slice your bread first, then wrap individual slices in plastic wrap and store in a freezer bag for up to 3 months. This way you can grab single servings whenever a craving hits.
Reheating Methods: For best results, reheat in a 350°F oven for 8-10 minutes wrapped in foil. This brings back that fresh-baked texture. Microwave works in a pinch (30-45 seconds per slice), but the crust won’t be as crispy. I sometimes pop reheated slices under the broiler for 1 minute to crisp up the top.
Troubleshooting Common Problems
Problem 1: Dough Won’t Rise
Your yeast might be dead or the water temperature was off. Check the expiration date on your yeast packet – old yeast won’t activate no matter what you do. If your water was too hot (over 120°F), it killed the yeast. Start over with fresh yeast and properly tempered water. Always proof your yeast first to confirm it’s alive before adding flour.
Problem 2: Cheese Leaking Out Everywhere
You didn’t seal the edges properly or rolled the dough too loosely. Make sure you’re leaving that ½-inch border and really pinching the seam closed. If cheese still escapes during baking, don’t panic – those crispy cheese bits on the pan are delicious scraped off and eaten as a baker’s treat.
Problem 3: Dough Too Sticky to Handle
The humidity in your kitchen affects flour absorption. Add flour one tablespoon at a time while kneading until the dough is tacky but not sticky. It should feel like a slightly moist balloon – you can touch it without it sticking to your hands.
Problem 4: Bottom Crust Soggy
Too much moisture from pepperoni grease or not baking long enough. Always pat your pepperoni dry, and make sure you’re baking on the middle rack where heat circulates best. If your bottom still seems soft, slide the bread onto the lower rack for the last 3-4 minutes of baking.
Problem 5: Bread Too Dense
You either didn’t knead enough or the dough didn’t rise properly. Kneading develops gluten which creates that soft, airy texture. Set a timer for 5 minutes of kneading – your arms might get tired, but the result is worth it. Also, make sure your rising spot is warm (around 75-80°F) but not hot.
Equipment Essentials

- Large mixing bowls (at least 2)
- Measuring cups and spoons
- Rolling pin (a wine bottle works if needed)
- Baking sheet (rimmed is best)
- Parchment paper (prevents sticking)
- Sharp knife or pizza cutter
- Pastry brush for butter
- Instant-read thermometer (optional but helpful)
- Kitchen towel for covering dough
Shopping List by Store Section
Baking Aisle:
- All-purpose flour
- Active dry yeast packets
- Sugar
Dairy Section:
- Shredded mozzarella cheese
- Butter
- Grated Parmesan cheese
Deli/Meat Section:
- Pepperoni slices
Produce Section:
- Fresh garlic
- Fresh parsley
Oils & Condiments:
- Olive oil
Spices:
- Salt
- Garlic powder
- Italian seasoning
- Red pepper flakes
Success Secrets from My Kitchen
1. Temperature Control Is Everything
Keep your ingredients at proper temperatures throughout the process. Cold cheese melts better than room temperature cheese, but room temperature dough is easier to roll than cold dough. I take my dough out to work with but keep my cheese refrigerated until the moment I need it.
2. The Flour Dusting Technique
When rolling out your dough, dust your rolling pin and work surface with flour frequently. A little flour goes a long way in preventing sticking. I keep a small bowl of flour next to my work area and dip my hands in it whenever the dough starts grabbing.
3. Sharp Tools Make Clean Cuts
A dull knife tears the dough instead of cutting it, which can cause your filling to leak. Before making those decorative slashes on top, sharpen your knife or use a razor blade for the cleanest cuts that won’t drag the dough.
4. The Resting Period Matters
Letting your bread rest for 5 minutes after baking isn’t just about safety – it’s chemistry. The cheese needs time to firm up slightly, and the dough continues cooking from residual heat. Cutting too early means cheese soup running everywhere.
5. Customize Your Spice Level
Start conservative with red pepper flakes if you’re not sure about heat tolerance. You can always serve extra flakes on the side, crushed with some dried oregano, so people can add more to their individual slices. I keep a small bowl of this mixture on the table whenever I serve pepperoni cheese bread.
Your pepperoni cheese bread is ready to steal the show at any gathering! The golden crust, stretchy cheese, and savory pepperoni create the perfect combination that works as an appetizer, snack, or even a fun dinner. Trust me, you’ll want to make a double batch – this disappears fast.



